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Tuesday, June 3, 2008

Live more than 100 years

The current documented record holder for longevity was Jeanne Calment, a French woman who lived 122 years and died in 1997. But you won't believe there is report of living 142 years old Bir Narayan Chaudhari in remote village of Nepal(died in 2001) but there is no enough documentation to verify the claims.

Art special man

Research suggests that centenarians have little in common physically. They are physically active people, most don’t smoke, and they typically maintained about the same body weight through their adult life.

The role of genetics in longevity is complex. A genetic vulnerability to a life threatening disease, e.g., malaria, reduces life expectancy. If a vaccine or cure is developed, the same genes no longer present a problem. With Alzheimer’s disease, for example, those with the certain apo-E gene patterns have a higher risk of developing Alzheimer’s. When scientists develop a cure, Alzheimer’s will no longer compromise the quality and length of life for those who are at risk.

There appear to be genes that foster living longer. Researchers have extended the life of fruit flies by 30% by giving them an extra copy of a gene. Other researchers extended the life of nematodes (microscopic worms) by 500% by removing a gene. It isn’t clear yet why the genetic engineering is extending the lives, but the results are promising.

Danish researchers compared identical and fraternal twins and extrapolated that only 30% of longevity is genetic. That means that 70% is lifestyle and the choices people make.

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